Simultaneous determination of regional cerebral blood flow, glucose metabolism, and pH in acute experimental allergic encephalomyelitis.

Regional Cerebral Glucose Metabolism and Regional Cerebral Blood Flow Changes in Temporal Lobe Structures in Schizophrenia : Measurements by Simultaneous F - 18 FDG and Tc 99 M HMPAO SPECT

Local cerebral glucose utilization during intracerebral pH changes.

The effect of ventriculocisternal perfusion with mock CSF with alkaline or acidic pH on the local CMRglu (LCMRglu) in the caudatoputamen was studied in artificially ventilated and relaxed rats. In control rats both lateral cerebral ventricles were perfused with mock CSF at pH 7.4. In the experimental series one cerebral ventricle was infused with normal mock CSF while the other was infused with...

Simultaneous measurement of blood flow and glucose metabolism by autoradiographic techniques.

A double tracer autoradiographic technique using 131I-iodo-antipyrine and 14C-deoxyglucose is presented for the simultaneous measurement of blood flow and cerebral glucose utilization in the same animal. 131I is a gamma emitting isotope with a half life of 8.06 days and can be detected with adequate resolution on standard autoradiographic films. Autoradiograms are made before and after decay of...

Simultaneous Measurement of Blood Flow and Glucose Metabolism

A double tracer autoradiographic technique using "'I-iodo-antipyrine and "C-deoxyglucose is presented for the simultaneous measurement of blood flow and cerebral glucose utilization in the same animal. '"I is a gamma emitting isotope with a half life of 8.06 days and can be detected with adequate resolution on standard autoradiographic films. Autoradlograms are made before and after decay of "'...

Contribution of Nitric Oxide Synthase (NOS) Activity in Blood-Brain Barrier Disruption and Edema after Acute Ischemia/ Reperfusion in Aortic Coarctation-Induced Hypertensive Rats

Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...